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Chicken Tetrazzini Recipe


  • Author: Luna
  • Total Time: 1 hour
  • Yield: 6 servings 1x

Description

This classic Chicken Tetrazzini is a comforting Italian-American casserole featuring tender seared chicken, sautéed mushrooms and onions, a creamy cheesy sauce, tender spaghetti, and melted mozzarella baked to bubbly perfection. It’s an easy all-in-one pasta bake perfect for hearty weeknight dinners or family gatherings.


Ingredients

Scale

Chicken

  • 1 large boneless skinless chicken breast
  • 2 teaspoons Italian Seasoning
  • Salt and Pepper to taste
  • 2 Tablespoons olive oil

Sauce

  • 2 Tablespoons butter
  • ¼ cup dry white wine
  • 8 oz. button mushrooms, diced
  • ½ yellow onion, diced
  • 3 cloves garlic, minced
  • 10.5 oz. cream of chicken soup
  • 10.5 oz. cream of mushroom soup
  • 1 cup sour cream
  • 1 cup milk
  • ¾ cup grated Parmesan cheese
  • 1 cup frozen peas

Pasta & Topping

  • ¾ lb. spaghetti
  • 2 cups mozzarella cheese
  • Fresh parsley, for garnish

Instructions

  1. Prepare the Chicken: Cut the chicken breast in half to create two thinner pieces. Season both sides with salt, pepper, and Italian seasoning. Heat olive oil in a large pot over medium-high heat and sear the chicken for 5-6 minutes per side until golden and fully cooked. Remove and let rest for 10 minutes before dicing into bite-sized pieces. Pour any chicken juices back into the pot.
  2. Preheat Oven: Set the oven to 350°F (175°C) to warm up for baking.
  3. Make the Sauce Base: In the same pot used for chicken, melt butter over medium heat. Add white wine and scrape the bottom of the pot with a spatula to loosen browned bits, then gently boil for 5 minutes to reduce.
  4. Sauté Vegetables: Add diced mushrooms and onion to the pot and sauté for about 5 minutes until softened. Stir in minced garlic and cook for another minute until fragrant.
  5. Combine Sauce Ingredients: Lower heat to medium-low. Stir in cream of chicken soup, cream of mushroom soup, Parmesan cheese, sour cream, milk, frozen peas, and the diced chicken pieces. Mix well and warm through on low heat.
  6. Cook Pasta: Boil spaghetti in salted water until just al dente, approximately 10 minutes. Drain well and return to the pot you boiled it in.
  7. Mix Pasta and Sauce: Pour the warm creamy chicken sauce over the drained spaghetti and stir thoroughly to combine all ingredients evenly.
  8. Assemble Casserole: Transfer the pasta mixture into a 9×13 inch casserole dish or large oven-safe pot. Evenly sprinkle the mozzarella cheese over the top.
  9. Bake: Bake uncovered at 350°F for 15 minutes. Then increase the oven temperature to 450°F and bake for an additional 10 minutes, or until the cheese is bubbly and golden brown.
  10. Serve: Let the casserole sit for 5 minutes to set before garnishing with fresh parsley. Serve warm and enjoy!

Notes

  • Use a dry white wine like Sauvignon Blanc or Pinot Grigio for best flavor; substitute with chicken broth if preferred.
  • For easier prep, day-old cooked chicken or rotisserie chicken can be used.
  • Be sure to not overcook the spaghetti during boiling; al dente texture holds better during baking.
  • Fresh parsley adds color and a bright herbal note—optional but recommended.
  • Prep Time: 20 minutes
  • Cook Time: 40 minutes
  • Category: Main Course
  • Method: Baking
  • Cuisine: Italian-American

Keywords: Chicken Tetrazzini, creamy chicken pasta bake, cheesy casserole, Italian-American comfort food, baked spaghetti casserole